Information below is from the below link as the credit must go to the author. https://pmc.ncbi.nlm.nih.gov/articles/PMC9151191 SUMMARY Since Ebola virus was discovered in 1970s, the virus has persisted in Africa and sporadic fatal outbreaks in humans and non-human primates have been reported. However, the evolutionary history of Ebola virus remains unclear. In a study, 27 Ebola virus strains with complete glycoprotein genes, including five species (Zaire, Sudan, Reston, Tai Forest, Bundibugyo)INTRODUCTIONThe family Filoviridae consists of two genera, Ebola virus (EBOV) and Marburg virus. According to the significant differences in the antigenicity and the nucleotide sequences, EBOV is subdivided into five species: Zaire (EBOV-Z), Sudan (EBOV-S), Reston (EBOV-R), Tai Forest (EBOV-TF, which was also known as Cote d’Ivoire ebola virus until 2010), and Bundibugyo (EBOV-B). However, EBOV-S, EBOV-Z, and EBOV-B often cause severe haemorrhagic diseases with markedly high case fatality rates. Due to the high biohazard risk, EBOV is classified as a BSL4 (biosafety level 4) agent based on high mortality rate, person-to-person transmission, potential aerosol infectivity, and absence of vaccines and therapies. Safe manipulation of EBOV requires maximum containment facilities.EBOVThe first three known outbreaks of EBOV occurred during the 1970s in the Democratic Republic of the Congo (DRC) and Sudan. No further cases were confirmed in Africa until late 1994. Since then, EBOV (EBOV-Z, EBOV-S, EBOV-TF, EBOV-B) has circulated in several African countries, including the Ivory Coast, DRC, Uganda, Republic of the Congo (RC), and Gabon (www.who.int). EBOV-R first emerged in the USA in 1989 from monkeys imported from the Philippines. The subsequent outbreaks in the USA in 1990, Italy in 1992, and the Philippines in 1996 are all traced back to the Philippines.Swine and monkeys are hosts of EBOV-R. Chimpanzees, gorillas, and humans are also well-known as hosts of EBOV-Z [9]. With regard to reservoirs, fruit bats thus far are confirmed as reservoirs of EBOV-Z m Previous analysis of GP, NP, and L genes of EBOV-Z suggests that all viruses have recent common ancestries regardless of the sampling dates, while EBOV is estimated to be at least 1000–2100 years old. These results, at least at first sight, appear to contradict each other. One explanation for these results is that EBOV-Z experienced a recent genetic bottleneck. However, it is unclear whether this explanation is viable or not.Since 1976 all EBOV-Z, EBOV-S, and EBOV-R strains traced back to around 1970, just at the time when the genetic diversity of EBOV declined to the lowest during its evolution history. https://pmc.ncbi.nlm.nih.gov/articles/PMC9151191 Uganda Ebola cases rises to 5 Cases rise in Ebola outbreak Rwanda Closes Border Crossings Questions about Ebola Is there a vaccine for Ebola ? Post navigation What are the symptoms for Ebola ? Is there a vaccine for Ebola ?
